There is strong evidence showing that luteolin has great effects on inhibiting the growth of cancer cells in Classical Hodgkin’s Lymphoma via caspase activated-cell death, which is characterized by the reduction of C-X-C chemokine receptor type 4 (CXCR4), matrix metalloproteinase (MMP)-2 and MMP-9 [220]. This evidence concerns the gene CXCR4 and cancer.