Apoptosis in DLBCL SU-DHL-4 cells was induced by 17-dimethylaminoethylamino-17-demethoxygeldanamycin, which can induce oxidative stress and then inhibit the expression of HSPA5 and Bcl-2 but promote the expression of Bax [22]. This evidence concerns the gene BAX and diffuse large B-cell lymphoma.