PTEN and pancreatic adenocarcinoma: In 2017, Omoto and colleagues [62] found that pancreatic adenocarcinoma and PNET showed significative differences (p < 0.005) in two TIC parameters: the values of peak intensity and the intensity at 60 s after contrast injection; these two parameters were significative lower in pancreatic adenocarcinoma than in PTEN (p < 0.05).