After multiple testing correction, the GG-genotype (rs879207, A > G) of TRPV1, a gene expressed in peripheral sensory neurons observed in 11.3% of the patients, was found to be associated with an increased risk of severe neuropathy (OR 5.2, 95%CI 2.1–12.8, FDR adjusted p-value 0.012). The gene discussed is TRPV1; the disease is neuropathy.