ERBB2 and neoplasm: Curcumin reduces the matrix metalloproteases’ (MMPs) enzyme production, chemokines, tyrosine kinase protein, inhibits N-terminal activity, the cell surface adhesive molecules NF-κβ, AP-1, TNF-α, LOX, and COX-2 and growth factors (HER-2 and EGFR) to inhibit the tumor invasion and progression.