Higher expression of RANBP3L was significantly associated with a lower histopathological grade (Grade 1) (p < 0.038 obtained by Fisher’s exact test); however, no significant association was found between RANBP3L expression and the other clinicopathological features such as: age, tumor size, histopathological subtype, PR and HER-2 status (see Table 7). This evidence concerns the gene PGR and neoplasm.