Systemic LF: Stimulation of antioxidant defense (increase of serum Cp, LF and catalase levels), decrease intensity of oxidative process (decreased serum MDA level), normalized the lymphocytic component of immunity (increased levels of lymphocytes in the peripheral blood), normalization hematological (Hb, erytrocytes and leukocytes levels) and biochemical (ALT, AST, creatinine, CRP) parameters in blood, resolution of polyorgan, primarily hepatic failure.Local LF:Regression of local proinflammatory processes. Here, GSTM1 is linked to liver failure.