SOD2 and metabolic dysfunction-associated steatotic liver disease: In addition to SAMM50, other oxidative stress-associated SNPs, such as rs4880 (C47T) in superoxide dismutase 2 (SOD2) [172,176] and rs1800849 (-55CT) in uncoupling protein 3 (UCP3) [178] genes, also associated with NAFLD, particularly with NASH.