CPSF2 and neoplasm: Sung et al. [23] univariately demonstrated that a tumor size ≥4 cm (2.72(1.07,6.92) p = 0.036) and a negative CPSF2 expression (0 and 1+) were significant predictors for regional metastasis, with a tumor size ≥ 4 cm being more significant, whereas in the multivariate analysis, negative CPSF2 expression (0 and 1+) remains the only predictor of regional metastases.