ACE2 and COVID-19: In this context, disturbances of the thyroid hormone responses are common in COVID-19 patients [3,4], since Angiotensin-converting enzyme 2 (ACE2), the functional receptor for SARS-CoV-2, plays a role in the pathogenesis of COVID-19 and is present at hypothalamic and pituitary structures [5] and in the thyroid gland [6].