BRCA1 and cancer: Yucer et al. generated induced-pluripotent-stem-cell-derived, fallopian tube epithelium organoids from healthy women and OC patients with germline pathogenic BReast CAncer 1 (BRCA1) mutations and found that BRCA1-mutated fallopian tube epithelium organoids showed cellular abnormalities consistent with OC genesis and progression, as well as exhibited an increased production of cancer-specific proteins and survival after xenotransplantation.