MAPK8 and renal carcinoma: Hish et al. and Chen et al. also showed that AsA suppressed human renal cancer cell migration and invasion via inhibition of the p-ERK/p-p38MAPK pathway [26], while AsA-induced apoptosis in cisplatin-resistant nasopharyngeal carcinoma cells was by activation of the p-JNK/p-p38MAPK pathway and inactivation of the p-ERK pathway [22].