As concerns NMSC, in the analysis by Khan et al. limited to BCC, neither anti-TNFα alone (an adjusted HR 1.27 (95% CI 0.84–1.90, P 5 0.26)) nor anti-TNFα in combination with thiopurines (adjusted HR 1.37 (95% CI 0.90–2.08, P 5 0.14)) was associated with a higher risk of BCC recurrence compared with 5-ASA [42]. Here, TNF is linked to skin basal cell carcinoma.