AKT1 and non-small cell lung carcinoma: Notably, the IC50 values for 7Bi to inhibit Akt-pS473 signals in NSCLC cells range from 1 to 10 μM and the IC50 values for 7Bi to suppress NSCLC cell growth are ~2.5 μM, thus further in-depth SAR (structure-activity relationship) studies are necessary to improve its potency.