Wang et al. reported that the expression of the lncRNA CCAT1, which is highly expressed in NSCLC cells, was down-regulated after irradiation, and its knockdown inhibited the mitogen-activated protein kinase pathway, which increased the radiosensitivity of NSCLC cells [22], while Ma et al. demonstrated that the lncRNA LINC00460 can promote gefitinib resistance in NSCLC cells by sponging miR-769-5p to modulate EGFR [23]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.