EGFR and non-small cell lung carcinoma: Consistent with these data, Maynard and colleagues used single-cell RNA sequencing (scRNA-Seq) to analyze tumor biopsies of EGFR-mutant NSCLC patients treated with osimertinib and showed that DTP cells are characterized by an alveolar-regenerative signature, which was related to activation of Wnt/β-catenin signaling [91].