The level of cyclophilin A, a member of the immunophilin family, was found to be significantly higher in both serum and exosomes from patients with NPC than from healthy individuals; further, when exosomal cyclophilin A and the antibody for EBV capsid antigen immunoglobulin A were combined, the diagnostic sensitivity and specificity were enhanced [115]. The gene discussed is PPIA; the disease is nasopharyngeal carcinoma.