Given that ACSL4 [15], GPX4 [16], SLC7A11 [17], ALDH3A2 [18], and HMGB1 [19] are representative ferroptosis-related genes, we first examined the expression of these genes in AML cell lines with circZBTB46 knockdown and overexpression. The gene discussed is ALDH3A2; the disease is acute myeloid leukemia.