PCSK1 and colorectal carcinoma: To test our hypothesis that ferroptosis may occur during NAB-induced CRC cell death, we used z-VAD (an apoptosis inhibitor), ferrostatin-1 (Fer-1, a potent ferroptosis specific inhibitor), necrostatin-1 (Nec-1, a potent necrotizing apoptosis inhibitor), and chloroquine (CQ, an effective autophagy inhibitor) to determine the types of programmed cell death induced by NaB.