EWSR1::FLI1 repressed miR-708 expression to indirectly induce EYA3 transcription [81], and inhibited expression of the tumor suppressive miR-145 [82,83], and other miRNAs including miR-22, miR29a, miR-100, miR-125b, miR-221/222 and miR-271 [84] to modulate tumor growth. The gene discussed is EYA3; the disease is neoplasm.