The cytokine C-C motif chemokine ligand 3 (CCL3), also known as macrophage inflammatory protein 1 alpha (MIP1A), functions in the tumor microenvironment by recruiting tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSC), thus creating an immunosuppressive environment and facilitating metastasis [31]. The gene discussed is CCL3; the disease is neoplasm.