CD8A and neoplasm: Although a direct comparison cannot be made, contrary to Sun et al., who observed CD8+ density > 97 cells/mm2 in the center of the tumor to be an independent predictor of longer DFS and OS [8], in our study CD8+ cell densities obtained by DIA within the entire malignant, non-malignant, and stroma compartments did not reveal an independent prognostic impact on OS or RFS[REF].