Platelet-derived mEVs from CRC patients incubated with HCT116 cells significantly induced TWIST1 (at 24 h) (Figure 5A) and VIM (at 4 and 24 h) (Figure 5C), and CDH1 was significantly downregulated (at 4 and 24 h) (Figure 5B). Here, TWIST1 is linked to colorectal carcinoma.