Except for UCEC tumors where the mutant variant was associated with a better prognosis (DFS, p = 0.044), DGCR8 mutation was globally found in patients with a worse outcome presenting COAD (DFS, p = 0.031, PFI, p = 0.031; OS, p = 0.031), CESC (DFS, p = 0.009; OS, p = 0.006) and ESCA (DFS, p = 0.021) cancer types (Figure 9). Here, DGCR8 is linked to cancer.