As for the other receptors analyzed in the CD56+ CD16+ NK cell population, no differences were observed between the different expression of NKp46, NKG2D and NKG2A (p = 0.647, 0.537 and 0.786, respectively), although there are some studies that correlated the concentration of circulating NK NKp46+ CD56dim cells in peripheral blood inversely with prognosis in NSCLC, without analyzing their response to immunotherapy [55]. The gene discussed is KLRK1; the disease is non-small cell lung carcinoma.