In this study, we utilized a bioinformatics analysis to identify potential oncogenes, which are overexpressed in CRC Interestingly, our results reveal that c-Met/GSK3β/MYC/CCND1 were among the top 25 differentially expressed genes (DEGs) in CRC, extracted from the GEO microarray datasets, GSE4107 and GSE41328. Here, GSK3B is linked to colorectal carcinoma.