Through computational simulation, we identified miR-26a bound to the 3′UTR of GSK3β/MYC/CCND1, thus suggesting a close association of Met/GSK3β/MYC/CCND1 and miR-26a promoting cancer proliferation, invasion, migration, drug resistance, and stemness metastasis in CRC patients. This evidence concerns the gene CCND1 and colorectal carcinoma.