TGFB1 and diabetic retinopathy: Furthermore, experimental models of diabetic retinopathy have shown that LncMALAT1, via associating with polycomb repressive complex 2 (PRC2) components, regulates the expression of several inflammatory genes [96], and LncRNA H19, via the TGF-β-mediated pathway, regulates endothelial-mesenchymal transition [110].