We applied the Oncoprint feature of cBioportal software, which revealed a volcano plot displaying overexpressed genes in CRC altered and unaltered cohorts, including (Figure 7A), we further explored the oncoprint to determine genetic mutations of the target oncogenes; VEGFA/CTNNB1/MMP7/CD44, which was based on percentages of separate genes due to amplification. The gene discussed is CD44; the disease is colorectal carcinoma.