CD44 and colorectal carcinoma: We further investigated the correlations among VEGFA/CTNNB1/MMP7/CD44 signatures and found that, when all four oncogenes were combined for analysis, the predicted results showed positive correlations in the range of r = 0.16~0.27 of VEGFA with CTNNB1 and MMP7 in CRC patients (Figure 5M–O), with positive Spearman and Pearson correlation coefficients and p < 0.05 considered statistically significant.