Examples for ascorbate efficacy include increased chemosensitivity of ovarian cancer associated with reduced chemotherapeutic toxicity and preferential killing of hepatocellular cancer stem cells involving sodium-dependent vitamin C transporter type 2 (SVCT2; SLC23A2), with very few cytotoxic effects on normal cells [30,31]. The gene discussed is SLC23A2; the disease is hepatocellular carcinoma.