MAPT and progressive supranuclear palsy: Moreover, mutations on the microtubule-associated protein tau (MAPT) gene have been implicated in many neurological disorders, including AD, corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), Pick’s disease (PiD), chronic traumatic encephalopathy (CTE), and frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17) [285,286].