Of these SNPs, seven were mapped in novel susceptibility genes for AD (EPPK1, TTLL1, PACSIN2, TPM4, PIF1, ZNF689 and AZGP1P1), two for PD (SLC26A1 and EFNA3) and two for MDD (HSPH1 and TRMT61A). This evidence concerns the gene PIF1 and Alzheimer disease.