This was evident by the presence of several molecules related to lipid regulation and catabolism in the SOD1-ALS pathway, such as SREBF2 (sterol regulatory element binding transcription factor 2), APOE (apolipoprotein E), PSAP (prosaposin), and LPL (lipoprotein lipase). The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.