Herein, we describe the association of HLA-A, B, C, DRB1, DRB345, DQA1, DQB1, DPA1, DPB1, and HLA-E, F, G, and H on the results of molecular detection of COVID-19, or, in some cases, on antibody detection upon first testing. Here, HLA-DQA1 is linked to COVID-19.