SOAT1 and systemic lupus erythematosus: The most significantly affected inflammation-related pathways in the case group were down-regulated MAPK, NLR, peroxisome, and systemic lupus erythematosus, and up-regulated leukocyte trans-endothelial migration, Wnt, JAK-STAT, and complement and coagulation cascades pathways (Figure 6H–K), all of which are associated with SLE, inflammatory response, blood vessel development, and glucocorticoid therapy.