ZMC1 (also known as NSC319726) was identified through a drug screen and shown to successfully induce apoptosis in ovarian cancer cell lines, likely through a two-pronged mechanism of (1) restoring proper WT p53 folding through the delivery of high amounts of zinc ion, and (2) the activation of apoptosis through the ROS (reactive oxygen species) pathway [153,159]. This evidence concerns the gene TP53 and ovarian cancer.