TP53 and ovarian carcinoma: In an older study, a cationic liposome (DDC) composed of dioleoyltrimethylamino propane (DOTAP), 1,2-dioeoyl-3-phosphophatidylethanolamine (DOPE), and cholesterol was formulated to deliver WT p53 DNA to OVCAR-3 ovarian cancer cells and nude mice [70].