ATP6AP2 and metabolic dysfunction-associated steatohepatitis: Representative images (Figure 3C) and quantification of Picrosirius Red-stained area (Figure 3D) showed that PRO20 significantly reduced collagen deposition following MCD treatment, reducing the total area to 6.0% ± 0.6% compared with 8.9% ± 0.2% for scrambled peptide (p < 0.0001), indicating that the PRR may regulate the onset of liver fibrosis in MCD diet-induced NASH.