The levels of the cytokines IFN-γ and IL-10 were higher in the TB group, showing that active infection by M. tuberculosis induces a strong reactive immune-inflammatory response, which can lead to the activation of different cell populations, characterized by an inflammatory, anti-inflammatory, or regulatory response, which can be specific or nonspecific for the eradication of the infection [48,49,50]. The gene discussed is IFNG; the disease is infection.