We therefore surveyed gastrointestinal pathogen loads, clinical outcome, colonic histopathology, and epithelial cell apoptosis in line with intestinal and systemic immune responses upon C. jejuni infection of microbiota-depleted IL-10−/− mice that had been pretreated with DESF via the drinking water starting a week prior infection in order to drain intestinal iron reservoirs. This evidence concerns the gene IL10 and infection.