According to the ICGC, GSE25097, GSE87630, and CCLE datasets (Figure 5C–F), the G6PD, SPP1, GLP1R, GAD1, MMP1, CCNA2, and MAPT were overexpressed in HCC tissues, while LCAT was lowly expressed in HCC tissues. The gene discussed is CCNA2; the disease is hepatocellular carcinoma.