In 2020, a study by Guo et al. found that downregulated miR-574-5p could inhibit ESCC cell proliferation and promote apoptosis via directly targeting Zinc finger protein 70 (ZNF70), and these functions were correlated with reactive oxygen species (ROS) generation and MAPK pathways [55]. Here, ZNF70 is linked to esophageal squamous cell carcinoma.