CALCOCO1 and colorectal carcinoma: These oncogenic effects were further investigated in another study in 2019, which indicated that miR-574-5p accelerated the migration and invasion of CRC cells by targeting downstream calcium-binding and coiled-coil domain 1 (CALCOCO1), whereas the non-coding RNA LINC00052 inhibited CRC metastasis via sponging miR-574-5p and modulating CALCOCO1 expression [52].