EZH1 and small cell lung carcinoma: As indicated in two studies, miR-574-5p partially exerted a protective effect as a long non-coding RNA (lncRNA) sponge, antagonizing the oncogenic lncRNA HOTTIP (HOXA transcript at the distal tip) and affecting the expression of downstream targets, such as enhancer of zeste homolog 1 (EZH1) protein and vimentin (VIM), ultimately alleviating SCLC cell growth, proliferation, and also EMT [22,23].