The RKFD group had a higher prevalence of metabolic syndrome and central obesity; higher levels of eGFR, eGFRcr-cys, urine albumin-creatinine ratio (UACR), fasting glucose, insulin, HOMA-IR, and FGF-23; and lower levels of total cholesterol, LDL, and serum creatinine than the group without RKFD. The gene discussed is ALB; the disease is metabolic syndrome.