ROC curves analysis for circulating miR-675 and tissue lncRNA-H19 (tumorous and non-tumorous) were performed and revealed that the sensitivity of miR-675 at cutoff ≥1.15 was significantly higher than tissue lncRNA-H19 at cutoff ≥1.37 for discriminating HCC from controls (95%, 89% respectively). This evidence concerns the gene H19 and hepatocellular carcinoma.