ALRN-6924 is a stabilized, cell-permeating antitumor peptide that disrupts p53 inhibition through mouse double minute 2 (MDM2) and MDMX and thereby restores normal P53 function and allows tumor cells to enter the apoptotic process in TP53-wild-type (WT) tumors [41]. This evidence concerns the gene TP53 and neoplasm.