In the last year, it was reported that ferroptosis suppressor protein 1 (FSP1) and the canonical glutathione-dependent GPx4 pathway are important to predict the efficacy of ferroptosis-inducing drugs (erastin and RSL3) in cancer [4,5] because these targets are associated with resistance to ferroptosis in epithelial ovarian cancer cells (OVCA). This evidence concerns the gene AIFM2 and ovarian carcinoma.