Inversely, levels of the DNA repair enzyme (hOGG1) in overweight hypertensive subjects were significantly lower, 0.02 ng/mL (0.01–0.6 ng/mL), p = 0.01 than overweight subjects without hypertension 0.5 ng/mL (0.3–3.0 ng/mL). This evidence concerns the gene LIG4 and Hypertension.