In detail, β-hydroxybutyrate secreted from adipocytes increases histone H3K9 acetylation and induces IL-1β and lipocalin 2 (LCN2) expression to enhance tumorigenicity in MCT2-expressing breast cancer cells, which in turn is linked to poor prognosis in breast cancer patients [54]. The gene discussed is SLC16A7; the disease is breast carcinoma.