TLR3 and infection: As observed in other fishes, the expression of TLR3 in the kidney of Prussian carp (Carassius auratus gibelio) reached a peak at 12 h after infection with cyprinid herpesvirus 2 (a dsDNA virus; [68]), and the transcript of TLR3 in golden pompano (Trachinotus ovatus) kidney also increased and first peaked at 6 h in response to a poly (I:C) stimulation [19].