MKI67 and neoplasm: Regarding the pathogenesis of PTBE in intracranial meningiomas, many influencing factors, including patient age, sex, tumor site and size, irregular tumor margin, disruption of the arachnoid plane, pial blood supply, signal intensity on T2-weighted MRI, Ki-67 index, histological subtype, and tumor grade, have been reported, some with very contradictory results [5–12].