Interestingly, we found significant overlaps of DEGs identified in both vGluT2+ and Gad2+ cerebellar neurons with DEGs in the cerebellum of a knock-in mouse model of Spinocerebellar ataxia 1 (SCA1) [OMIM:164400], an autosomal dominant disease caused by expansion of a polyglutamine encoding CAG repeat in the Ataxin1 gene (Atxn1) (Fig. S8) [39]. This evidence concerns the gene ATXN1 and autosomal dominant disease.