Mgrditchian et al. [60] used syngeneic melanoma B16-F10 model and found that inhibition of autophagy (by Beclin 1 depletion) resulted in a C-C motif chemokine ligand 5 (CCL5)-mediated NK cell homing at the tumor sites, which might contribute to reduced tumor volume. This evidence concerns the gene BECN1 and neoplasm.